Liste des publications

2023

• Concerted conformational changes control metabotropic glutamate receptor activity

  Lecat-Guillet N, Quast RB, Liu H, Bourrier E, Moller TC, Rovira X, Soldevila S, Lamarque L, Trinquet E, Liu J, Pin JP, Rondard P, Margeat E, Sci Adv, 2023

• Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins

  Agam G, Gebhardt C, Popara M, Machtel R, Folz J, Ambrose B, Chamachi N, Chung SY, Craggs TD, de Boer M, Grohmann D, Ha T, Hartmann A, Hendrix J, Hirschfeld V, Hubner CG, Hugel T, Kammerer D, Kang HS, Kapanidis AN, Krainer G, Kramm K, Lemke EA, Lerner E, Margeat E, Martens K, Michaelis J, Mitra J, Moya Munoz GG, Quast RB, Robb NC, Sattler M, Schlierf M, Schneider J, Schroeder T, Sefer A, Tan PS, Thurn J, Tinnefeld P, van Noort J, Weiss S, Wendler N, Zijlstra N, Barth A, Seidel CAM, Lamb DC, Cordes T, Nat Methods, 2023

2022

• A modular spring-loaded actuator for mechanical activation of membrane proteins

  Mills A, Aissaoui N, Maurel D, Elezgaray J, Morvan F, Vasseur JJ, Margeat E, Quast RB, Lai-Kee-Him J, Saint N, Benistant C, Nord A, Pedaci F, Bellot G, Nat Commun, 2022

• Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations

  Nasrallah C, Cannone G, Briot J, Rottier K, Berizzi AE, Huang CY, Quast RB, Hoh F, Baneres JL, Malhaire F, Berto L, Dumazer A, Font-Ingles J, Gomez-Santacana X, Catena J, Kniazeff J, Goudet C, Llebaria A, Pin JP, Vinothkumar KR, Lebon G, Cell Rep, 2022

2021

• Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state

  Cao AM, Quast RB, Fatemi F, Rondard P, Pin JP, Margeat E, Nat Commun, 2021

• Single-molecule FRET on its way to structural biology in live cells

  Quast RB, Margeat E, Nat Methods, 2021

2019

• Studying GPCR conformational dynamics by single molecule fluorescence

  Quast RB, Margeat E, Mol Cell Endocrinol, 2019

• Accurate Determination of Human CPR Conformational Equilibrium by smFRET using Dual Orthogonal Non-Canonical Amino Acid Labeling

  Quast RB, Fatemi F, Kranendonk M, Margeat E, Truan G, Chembiochem, 2019